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Usage of the medication sildenafil - better identified to most because the model-title drug Viagra - is associated with dramatically diminished incidence of Alzheimer's illness, new analysis suggests. In accordance with a research led by researchers on the Cleveland Clinic, taking sildenafil is tied to a nearly 70 % decrease danger of developing Alzheimer's compared to non-customers. That's based mostly on an analysis of medical health insurance declare information from over 7.2 million people, through which information showed that claimants who took the treatment were a lot much less likely to develop Alzheimer's over the subsequent six years of observe up, compared to matched management patients who didn't use sildenafil. VIAGRA- Sildenafil Citrate Tablet, Film Coated." U.S. Co-administration of the HIV protease inhibitor ritonavir, which is a extremely potent P450 inhibitor, at steady state (500 mg twice day by day) with sildenafil (a hundred mg single dose) resulted in a 300% (4-fold) enhance in sildenafil Cmax and a 1 000% (11-fold) increase in sildenafil plasma AUC.